Improving Glycoenzymes using Synthetic Biology

October 17, 2024

On July 18, 2025, Sriram Neelamegham and team at the State University of New York, Buffalo published a paper titled "Engineering glycosyltransferases into glycan binding proteins using a mammalian surface display platform" in Nature Communications. This paper successfully engineered a mammalian glycosyltransferase (GT) to function as a highly specific glycan-binding protein (GBP). This work demonstrates […]

December 9, 2025

On Jun 21, 2021, Nguyen et al. from the Bioprocessing Technology Institute (BTI) at the Agency for Science, Technology and Research (A*STAR) in Singapore, published a paper in the Scientific Reports, titled "Multiplexed engineering glycosyltransferase genes in CHO cells via targeted integration for producing antibodies with diverse complex-type N-glycans." The research group developed a robust […]