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Engineering Glycosyltransferases into Glycan-binding Proteins Using a Mammalian Surface Display Platform

Improving Glycoenzymes using Synthetic Biology

Engineering Glycosyltransferases into Glycan-binding Proteins Using a Mammalian Surface Display Platform
October 17, 2024
Engineering Glycosyltransferases into Glycan-binding Proteins Using a Mammalian Surface Display Platform

On July 18, 2025, Sriram Neelamegham and team at the State University of New York, Buffalo published a paper titled "Engineering glycosyltransferases into glycan binding proteins using a mammalian surface display platform" in Nature Communications. This paper successfully engineered a mammalian glycosyltransferase (GT) to function as a highly specific glycan-binding protein (GBP). This work demonstrates […]

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