Fueling Innovation with Insect Chassis in Synthetic Biology

Synthetic biology is a technology in which people link "genes" into networks, allowing cells to perform various tasks envisioned by designers. Among them, the genome of insect chassis cells is more complex, which is expected to be a good biological cell chassis. As a company specializing in the field of biology, CD BioGlyco keeps up with the trend of biology development and continues to develop synthetic biology technology and GlycoChas™ platforms to provide professional insect chassis cell engineering services.

Professional Insect Chassis Cell Engineering Services

• Insect chassis cell factory
  We utilize highly efficient gene editing technology to design and reprogram the metabolic regulatory network of insect chassis cells using a bottom-up strategy.
  At the same time, we harmonize the biosynthetic routes of target products with the metabolic pathways of insect chassis cells materially and energetically to construct insect cell factories with good performance.
• Gene editing in chassis cells
  Gene editing is a key tool in the construction process of insect chassis cell engineering, and we utilize a variety of chassis cell gene delivery and editing systems that allow for precise cleavage and targeted insertion of target genes.
  • Transcription activator-like effector nuclease (TALEN) technology: Knock-in (KI) of insect chassis cells and modification and design of insect proteins
  • Clustered regulatory interspaced short palindromic repeat (CRISPR) system: This system enables knockdown (KD) of insect cells, manipulation of genes in specific genomes, and design and modification of insect DNA (rDNA) and RNA (rRNA)
  • Microarray synthesis technology: Accomplishing high-throughput gene synthesis

Here, we offer several types of insect chassis cell engineering services to our clients.

Applications

• Insect cells are versatile expression hosts for recombinant proteins, which can be used for the production of highly active proteins, and can also be utilized in a variety of disciplines such as biophysics and biochemistry.
• Insect chassis cells are used for structural analysis of active proteins, drug design, and development of diagnostic reagents.
• Insect chassis cells can be used to produce vaccines. For example, insect cell lines are capable of producing HPV vaccines in the form of virus-like particles.

Advantages

• We have established a state-of-the-art chassis cell platform to provide our clients with multiple types of chassis cells for use in synthetic biology.
• We have a diverse portfolio of disciplines that enable us to realize a wider range of chassis cell engineering applications through different combinations of technologies.
• We focus on providing cost-effective solutions to ensure that our clients receive the best possible service.

CD BioGlyco is a specialized biology company skilled in advanced synthetic biology technologies. Our technology staff keeps abreast of cutting-edge technological developments and maintains a continuous development of new technologies, processes, and products. If you are interested in our services or products, please feel free to contact us.

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