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On May 26, 2025, Hao, Liao, and Lyu from the State Key Laboratory of Pathogen and Biosecurity at the Beijing Institute of Biotechnology published a paper titled "Biosynthesis of Two Types of Exogenous Antigenic Polysaccharides in a Single Escherichia coli Chassis Cell" in Life. This work introduces a robust Synthetic Biology Platform that successfully engineers […]

On July 8, 2025, Bidstrup et al., representing institutions such as Cornell University, the University of Maryland, and Stanford University, published a paper entitled "Glycosylation of Structured Protein Domains in Cell-Free Reaction Environments" in ACS Synthetic Biology. The article addresses a fundamental limitation in biomanufacturing: the challenge of predictably attaching N-linked glycans to protein targets […]

On July 18, 2025, Sriram Neelamegham and team at the State University of New York, Buffalo published a paper titled "Engineering glycosyltransferases into glycan binding proteins using a mammalian surface display platform" in Nature Communications. This paper successfully engineered a mammalian glycosyltransferase (GT) to function as a highly specific glycan-binding protein (GBP). This work demonstrates […]

On March 19, 2024, Bao et al. from Dalian University in China published a paper titled "Construction of an Escherichia coli chassis for efficient biosynthesis of human-like N-linked glycoproteins" in Frontiers in Bioengineering and Biotechnology. This paper details the successful construction of a stable, high-performance Escherichia coli Chassis cell factory designed for the efficient biosynthesis […]